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While traditional neurotoxins like Botox and Dysport have been the industry standard for years, DAXXIFY® (daxibotulinumtoxinA-lanm) is the first and only FDA-approved, peptide-formulated frown line treatment. At Trifecta Med Spa, we specialize in "Zero-Filter Luxury"—providing results that look natural, radiant, and incredibly long-lasting.

Trifecta Med Spa is consistently recognized among the top 100 aesthetic practices in the United States, placing us in the elite 1% of high-volume injectors nationwide.
Under the medical direction of Dr. Edward Fruitman, M.D., our 'Expertise First' model ensures that every DAXXIFY® treatment is performed with surgical-grade anatomical precision.
We utilize ultra-fine, premium-gauge needles and a specialized comfort technique to ensure your NYC Daxxify session is virtually painless with no downtime.
We specialize in 'Quiet Luxury'—a customized injection mapping technique designed to give you a refreshed, wide-awake look while maintaining full natural expression.
Experience the transformation. Daxxify works quickly—many patients see a visible improvement in just 1 to 2 days.



Real Daxxify patients showing the softening of moderate to severe glabellar lines (frown lines) 2 weeks post-treatment.
Daxxify is exceptionally effective at treating dynamic wrinkles caused by repetitive facial expressions. At Trifecta, we use it to treat:

The vertical lines between your eyebrows that can make you look tired or angry.
Horizontal lines across the brow for a smoother, more youthful forehead.
Fine lines around the outer corners of the eyes.
Small wrinkles on the bridge of the nose.
A subtle lift to open up the eyes and create a more awake appearance.
Slims the jawline and helps alleviate symptoms of teeth grinding (TMJ).
Relaxes the upper lip to create a fuller, more defined appearance without filler.
Smooths the neck and jawline for a more contoured and youthful profile.
| Feature | DAXXIFY® | Botox® Cosmetic | Dysport® |
|---|---|---|---|
| Active Ingredient | DaxibotulinumtoxinA | OnabotulinumtoxinA | AbobotulinumtoxinA |
| Stabilizer | Proprietary Peptide | Human Serum Albumin | Human Serum Albumin |
| Avg. Longevity | 5–6 Months | 3–4 Months | 3–4 Months |
| Onset of Action | 1–2 Days | 5–7 Days | 3–4 Days |
| Best For | Maximum longevity & "glow" | Precision & versatility | Fast onset & larger areas |
Daxxify is a premium injectable neurotoxin used to temporarily smooth moderate to severe wrinkles. It is unique because it uses a peptide to deliver the toxin to the nerve cells, rather than the human blood products used in older formulas.
"Better" depends on your goals. If you are tired of visiting the med spa every 3 months, Daxxify is a superior choice because it can last twice as long. It is also an excellent option for patients who have developed a "Botox resistance."
Daxxify typically has a higher upfront cost than Botox because the results last significantly longer. At Trifecta Med Spa, we price Daxxify to reflect its value—fewer appointments per year means more time and convenience for you.
The most common side effects are similar to other injectables: mild headache, slight swelling, or redness at the injection site. These usually resolve within 24–48 hours.
To minimize bruising, we recommend avoiding alcohol and blood-thinning supplements (like fish oil or ibuprofen) for 3–5 days before your treatment at our NYC or Long Island clinics.
Stop settling for 3-month results. Join the "Quiet Luxury" movement and see why Daxxify at Trifecta Med Spa is the top choice for savvy New Yorkers.
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